Toltrazuril (Toltraneer) induces
swell of endoplasmic reticulum and Golgi apparatus in the somatic cell during
the normal development stages of coccidia, and leads to abnormal distribution
of the space around the nucleus. Toltrazuril inhibits the enzymatic activity of
respiratory chain for coccidia and oxidative phosphorylation in mitochondrial
of coccidia. Therefore, the respiratory action of coccidia is interfered, which
affects the normal metabolism of it and leads to the death. Furthermore, the
cell wall structure of macrogametocyte for Eimeria is interfered and releasing
process is blocked thus the oocyst can not be formed. Toltrazuril is effective
against of all intracellular development stages.
Ø The latest synthetic agent with high efficiency for
anticoccidiosis, and anticoccidiosis index over 180, which is effective against
the 6 types of main Eimeria species in poultry such as E. tenella,
brunetti, E. maxima, E. mitis.
against all intracellular development stages of coccidia.
and effective way of anticoccidiosis and 2 days needed for coccidia killing.
Ø Good palatability, less toxicity and side effects,
and not interfere with the immunity production of livestock and poultry.
effects with broad-spectrum of anticoccidiosis, but not easy to be produced drug
product can be maintained stable after dilution within 48 hours.
Ø Safe and convenient by oral administration.
Ø Maintain normal
feed and water intake
for livestock and poultry.
reduction of death rate, promote rapid recovery from diseases and improve
It is highly efficacious
coccidiocidal against all intracellular stages(shizogony and gametogony) of all
important Eimeria species & all avian
species. Toltraneer causes cidal changes in the organelles of the parasite at
multiple levels. It has been used not only during clinical outbreaks of
coccidiosis but also as a strategic methaphylactic treatment to prevent the
appearance of subclinical coccidiosis, as a post-vaccinal treatment &
lately as a stand-alone treatment. Besides, It is also effective against E.
adenoides, E meleagrimitis, E gallopavonis in Turkey.
It should not be administered in flocks with
impaired hepatic and renal function, should not be used in animal
hypersensitive to active ingredient.
It is compatible to with other poultry additives
& no hazardous reactions of animal were reported.
USAGE AND ADMINISTRATION:
7mg Toltraneer per kg body weight per day for 2
consecutive days or 1ml/liter of drinking water for 2 consecutive days or
28ml/100kg body weight for 2 consecutive days , the treatment can be repeated 5
days later. 140ml/500kg body weight for 2 consecutive days, the treatment can
be repeated 5 days later.
STORAGE AND PRECAUTION:
a cool and dry place & protect from heat and light & prevent from insect. Keep
out of the reach of children.
PACKING: 100ml, 500ml, 1L or according to request of customer.